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The Opioid Epidemic and Infectious Diseases E- Book

The Opioid Epidemic and Infectious Diseases E- Book
  • Author : Brianna L. Norton
  • Publisher :Unknown
  • Release Date :2020-10-25
  • Total pages :300
  • ISBN : 9780323683296
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Summary : Offering timely guidance on the junction of the opioid crisis and infectious diseases, this practical handbook by Dr. Brianna L. Norton provides concise yet comprehensive coverage of a growing patient population. Infectious disease specialists are increasingly seeing patients who previously used opiods and now use intravenous drugs. Many challenges are unique to this patient population, including new and growing infections such as hepatitis C, endocarditis, HIV, and hepatitis B. The Opioid Epidemic and Infectious Diseases is an up-to-date, real-world guide that covers the scope of the problem, management guidelines, and much more. Describes the new landscape of the opioid crisis in the U.S. and its intersection with infectious diseases, including epidemiology, Opioid Use Disorder (OUD) and rural America, and more. Offers practical guidance on (OUD) and infectious co-morbidities like hepatitis C, STDs, endocarditis, HIV, and hepatitis B. Covers prevention, treatment, and harm reduction. Discusses OUD, infectious diseases, and the criminal justice system. Consolidates today’s available information and guidance into a single, convenient resource.

The Opioid Epidemic and Infectious Diseases

The Opioid Epidemic and Infectious Diseases
  • Author : Brianna L. Norton
  • Publisher :Unknown
  • Release Date :2020-10-27
  • Total pages :304
  • ISBN : 0323683282
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Summary : Offering timely guidance on the junction of the opioid crisis and infectious diseases, this practical handbook by Dr. Brianna L. Norton provides concise yet comprehensive coverage of a growing patient population. Infectious disease specialists are increasingly seeing patients who previously used opiods and now use intravenous drugs. Many challenges are unique to this patient population, including new and growing infections such as hepatitis C, endocarditis, HIV, and hepatitis B. The Opioid Epidemic and Infectious Diseases is an up-to-date, real-world guide that covers the scope of the problem, management guidelines, and much more. Describes the new landscape of the opioid crisis in the U.S. and its intersection with infectious diseases, including epidemiology, Opioid Use Disorder (OUD) and rural America, and more. Offers practical guidance on (OUD) and infectious co-morbidities like hepatitis C, STDs, endocarditis, HIV, and hepatitis B. Covers prevention, treatment, and harm reduction. Discusses OUD, infectious diseases, and the criminal justice system. Consolidates today's available information and guidance into a single, convenient resource.

Opportunities to Improve Opioid Use Disorder and Infectious Disease Services

Opportunities to Improve Opioid Use Disorder and Infectious Disease Services
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Examination of the Integration of Opioid and Infectious Disease Prevention Efforts in Select Programs
  • Publisher :Unknown
  • Release Date :2020-04-30
  • Total pages :216
  • ISBN : 9780309654494
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Summary : Opioid use and infectious diseases are intertwined epidemics. Despite the fact that the United States is more than two decades into the opioid crisis - the cause of tens of thousands of deaths every year on its own - the health system has not sufficiently addressed the morbidity and mortality of drug use coupled with infectious diseases. This is at least in part due to traditional models of substance use disorder care wherein substance use disorder treatment is delivered independently of other medical care, thereby inhibiting the delivery of comprehensive care. As a result, the United States is experiencing a drastic increase in infectious diseases that spread with drug use. Opportunities to Improve Opioid Use Disorder and Infectious Disease Services examines current efforts to integrate care and describes barriers, such as inadequate workforce and training; lack of data integration and sharing; and stigma among people who use drugs and have also been diagnosed with an infectious disease. The conclusions and recommendations of this report will help to promote patient-centered, integrated programs to address this dual epidemic.

Integrating Responses at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics

Integrating Responses at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice
  • Publisher :Unknown
  • Release Date :2018-09-27
  • Total pages :174
  • ISBN : 9780309477949
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Summary : According to the Centers for Disease Control and Prevention (CDC), 115 Americans die each day from an opioid overdose, which averages one death every 12.5 minutes. Between 1999 and 2016, the number of drug overdoses catapulted by 300 percent, with injection drug use increasing by 93 percent between 2004 and 2014 and opioid-related hospital admissions increasing by 58 percent over the past decade. And an inexorable sequela of the opioid epidemic is the spread of infectious diseases. To address these infectious disease consequences of the opioid crisis, a public workshop titled Integrating Infectious Disease Considerations with Response to the Opioid Epidemic was convened on March 12 and 13, 2018, by the National Academies of Sciences, Engineering, and Medicine. Participants discussed strategies to prevent and treat infections in people who inject drugs, especially ways to work efficiently though the existing public health and medical systems. This publication summarizes the presentations and discussions from the workshop.

Integrating Responses at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics

Integrating Responses at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice
  • Publisher :Unknown
  • Release Date :2018-08-27
  • Total pages :174
  • ISBN : 9780309477970
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Summary : According to the Centers for Disease Control and Prevention (CDC), 115 Americans die each day from an opioid overdose, which averages one death every 12.5 minutes. Between 1999 and 2016, the number of drug overdoses catapulted by 300 percent, with injection drug use increasing by 93 percent between 2004 and 2014 and opioid-related hospital admissions increasing by 58 percent over the past decade. And an inexorable sequela of the opioid epidemic is the spread of infectious diseases. To address these infectious disease consequences of the opioid crisis, a public workshop titled Integrating Infectious Disease Considerations with Response to the Opioid Epidemic was convened on March 12 and 13, 2018, by the National Academies of Sciences, Engineering, and Medicine. Participants discussed strategies to prevent and treat infections in people who inject drugs, especially ways to work efficiently though the existing public health and medical systems. This publication summarizes the presentations and discussions from the workshop.

Integrating Responses at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics

Integrating Responses at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2018
  • Total pages :157
  • ISBN : 0309477956
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Summary : "According to the Centers for Disease Control and Prevention (CDC), 115 Americans die each day from an opioid overdose, which averages one death every 12.5 minutes. Between 1999 and 2016, the number of drug overdoses catapulted by 300 percent, with injection drug use increasing by 93 percent between 2004 and 2014 and opioid-related hospital admissions increasing by 58 percent over the past decade. And an inexorable sequela of the opioid epidemic is the spread of infectious diseases. To address these infectious disease consequences of the opioid crisis, a public workshop titled Integrating Infectious Disease Considerations with Response to the Opioid Epidemic was convened on March 12 and 13, 2018, by the National Academies of Sciences, Engineering, and Medicine. Participants discussed strategies to prevent and treat infections in people who inject drugs, especially ways to work efficiently though the existing public health and medical systems. This publication summarizes the presentations and discussions from the workshop"--Publisher's description

Pain Management and the Opioid Epidemic

Pain Management and the Opioid Epidemic
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse
  • Publisher :Unknown
  • Release Date :2017-09-28
  • Total pages :482
  • ISBN : 9780309459570
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Summary : Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Infections in IV Drug Users, An Issue of Infectious Disease Clinics of North America, E-Book

Infections in IV Drug Users, An Issue of Infectious Disease Clinics of North America, E-Book
  • Author : Carlos Del Rio,Sandra Springer
  • Publisher :Unknown
  • Release Date :2020-08-31
  • Total pages :240
  • ISBN : 9780323777865
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Summary : Together with Consulting Editor, Dr. Helen Bucher, Guest Editors Dr. Carlos Del Rio and Dr. Sandra Springer have put together an important monograph that addresses infections in IV drug users. They have selected top experts to contribute clinical reviews for infectious disease physicians. Articles are devoted to the following topics: Medical and Surgical management of Infectious endocarditis in persons who use drugs; The Microbiology Laboratory and the Opioid epidemic; The Geography of Infectious Diseases Related to the Opioid Epidemic; Soft tissue, bone and joint infections related to illicit drug use; Management of opioid use disorder and infectious disease in the inpatient setting; Outpatient antimicrobial and OUD management in persons who use drugs; Novel approaches to antimicrobials for injection drug use associated infections; HCV treatment and reinfection risk in persons who use drugs on medication treatment for OUD: A systematic review in CJS settings; Treating opioid use disorder and related infectious diseases in the criminal justice system; Harm reduction services to prevent and treat infectious disease in persons who use drugs; Improving the management of patients with chronic opioid therapy in the outpatient setting; The Global Task Force for Chronic Pain in People Living with HIV (PLWH): Developing a research agenda in an emerging field; and Lessons learned from the response to the HIV epidemic that can inform addressing the opioid epidemic. Readers will come away with the clinical information they need to treat and improve outcomes in these patients.

Infectious Diseases and Substance Abuse

Infectious Diseases and Substance Abuse
  • Author : Herman Friedman,Thomas W. Klein,Mauro Bendinelli
  • Publisher :Unknown
  • Release Date :2006-05-28
  • Total pages :212
  • ISBN : 9780306486883
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Summary : The use of recreational drugs of abuse by large numbers of individuals in this country and abroad has aroused serious concerns about the consequences of this activity. For example, it is recognized that marijuana is currently widely used as a recreational drug in the United States as well as other countries. Similarly, abuse of cocaine, especially crack cocaine, is considered to be an epidemic. “The war on drugs” by the US Government was directly aimed at the illicit use of cocaine, marijuana, and opiates as well as other drugs of abuse. Furthermore, alcohol is also considered a major problem of abuse in this country as well as in many other countries. It is estimated there are at least 10 million alcoholics in the United States alone. A signi?cant portion of those hospitalized with infectious diseases are alcoholics. Similarly, there have been many reports of association between marijuana use and increased susceptibility to infection as well as a re- tion between use of opiates and infections. The relationship between drug abuse and increased incidence of various infections has stimulated increased investi- tion of whether and how such drugs affect immune function, especially imp- tant for resistance against infectious agents. During the last decades, a wide variety of studies have shown that drugs of abuse, including marijuana, cocaine, or opiates, as well as alcohol, alter both neurophysiological as well as pathological responses of individuals.

Medications for Opioid Use Disorder Save Lives

Medications for Opioid Use Disorder Save Lives
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Medication-Assisted Treatment for Opioid Use Disorder
  • Publisher :Unknown
  • Release Date :2019-06-16
  • Total pages :174
  • ISBN : 9780309486484
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Summary : The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

Identifying Safety-net Resources at Health Centers to Prevent Infectious Disease Transmission Resulting from the Opioid Epidemic

Identifying Safety-net Resources at Health Centers to Prevent Infectious Disease Transmission Resulting from the Opioid Epidemic
  • Author : Joshua Breslau
  • Publisher :Unknown
  • Release Date :2019
  • Total pages :32
  • ISBN : OCLC:1110462549
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Summary : The Assistant Secretary for Planning and Evaluation for the U.S. Department of Health and Human Services asked the RAND Corporation to conduct an exploratory study examining the factors that affect the ability of Community Health Centers (CHCs) to reduce transmission of infectious diseases related to the opioid epidemic. The emphasis is on rural areas, which have suffered disproportionately from the opioid epidemic and lack resources to address the complex social and medical issues related to opioid use, opioid use disorder, and risk for infectious diseases. Discussions were held with staff from eight CHCs, selected from the 102 CHCs in counties that prior research has identified as being at high risk for opioid-use related transmission of infectious diseases. The content of these discussions was summarized to identify the major challenges that CHCs face in preventing and treating infectious diseases and the strategies that they employ to overcome these strategies.

Infections in IV Drug Users, an Issue of Infectious Disease Clinics of North America

Infections in IV Drug Users, an Issue of Infectious Disease Clinics of North America
  • Author : Carlos Del Rio,Sandra Springer
  • Publisher :Unknown
  • Release Date :2020-09-30
  • Total pages :240
  • ISBN : 0323777856
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Summary : Together with Consulting Editor, Dr. Helen Bucher, Guest Editors Dr. Carlos Del Rio and Dr. Sandra Springer have put together an important monograph that addresses infections in IV drug users. They have selected top experts to contribute clinical reviews for infectious disease physicians. Articles are devoted to the following topics: Medical and Surgical management of Infectious endocarditis in persons who use drugs; The Microbiology Laboratory and the Opioid epidemic; The Geography of Infectious Diseases Related to the Opioid Epidemic; Soft tissue, bone and joint infections related to illicit drug use; Management of opioid use disorder and infectious disease in the inpatient setting; Outpatient antimicrobial and OUD management in persons who use drugs; Novel approaches to antimicrobials for injection drug use associated infections; HCV treatment and reinfection risk in persons who use drugs on medication treatment for OUD: A systematic review in CJS settings; Treating opioid use disorder and related infectious diseases in the criminal justice system; Harm reduction services to prevent and treat infectious disease in persons who use drugs; Improving the management of patients with chronic opioid therapy in the outpatient setting; The Global Task Force for Chronic Pain in People Living with HIV (PLWH): Developing a research agenda in an emerging field; and Lessons learned from the response to the HIV epidemic that can inform addressing the opioid epidemic. Readers will come away with the clinical information they need to treat and improve outcomes in these patients.

A Public Health Guide to Ending the Opioid Epidemic

A Public Health Guide to Ending the Opioid Epidemic
  • Author : Jay C. Butler,Michael R. Fraser
  • Publisher :Unknown
  • Release Date :2019-10-02
  • Total pages :336
  • ISBN : 9780190056834
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Summary : THE DEFINITIVE GUIDE FOR PUBLIC HEALTH PROFESSIONALS FIGHTING THE OPIOID EPIDEMIC The opioid crisis has devastated families and communities across the United States. Changes in policing and medical practices have been swift, but they've achieved only a modest impact on the fundamental causes of substance misuse and addiction. The necessity for upstream intervention is clear. But what does that look like? A Public Health Guide to Ending the Opioid Epidemic does what only a public health approach can: offer credible, scalable, and empirically supported approaches to uprooting one of society's most pernicious challenges. It systemizes the core tenets of the public health approach to substance misuse and addiction, which alongside clinical approaches (prescription guidelines and monitoring, increased access to overdose-reversal medication, and medication-assisted treatment availability) offers a roadmap for end-to-end response to this diverse problem. Core elements of the public health approach, all covered here in practical terms, include: · How to support community-based, primary prevention of substance misuse and addiction in different settings and populations · How to effectively address the cultural, social, and environmental aspects of health that are driving the current epidemic · How governmental public health agencies play a significant role in responding to the epidemic, both in the field's traditional model of disease surveillance and control and in more directed approaches to health promotion (building community resilience; addressing the impact of adverse childhood events; mitigating the root causes of addiction) These frameworks offer a foundation for understanding, analyzing, and meaningfully impacting the burden of opioid misuse and addiction in any population or setting. A Public Health Guide to Ending the Opioid Epidemic is a roadmap for meaningful change.

Avoiding Opioid Abuse While Managing Pain

Avoiding Opioid Abuse While Managing Pain
  • Author : Lynn R. Webster,Beth Dove
  • Publisher :Unknown
  • Release Date :2007-06
  • Total pages :202
  • ISBN : 9781934716281
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Summary : A guide for clinicians who prescribe opioids. Sorts out the clinical, regulatory, and ethical issues associated with prescribing opioid analgesics.

A National Strategy for the Elimination of Hepatitis B and C

A National Strategy for the Elimination of Hepatitis B and C
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on a National Strategy for the Elimination of Hepatitis B and C
  • Publisher :Unknown
  • Release Date :2017-06-30
  • Total pages :296
  • ISBN : 9780309457323
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Summary : Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the second of two, builds off the conclusions of the first report and outlines a strategy for hepatitis reduction over time and specific actions to achieve them.

A Public Health Guide to Ending the Opioid Epidemic

A Public Health Guide to Ending the Opioid Epidemic
  • Author : BUTLER & FRASER (EDS)
  • Publisher :Unknown
  • Release Date :2021
  • Total pages :229
  • ISBN : 0190056843
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Summary : Few contributions to the field concerning the current opioid crisis in the United States focus sufficient attention on the public health aspects of the epidemic and share examples that practitioners can use to prevent opioid use disorder and the broader issues of substance misuse and addiction. A great deal of prior published work has concentrated on health care and clinical perspectives related to the crisis, including developing prescribing guidelines, enhancing prescription drug monitoring programs, scaling up access to overdose reversal medication, and making medication-assisted treatment more widely available nationwide. This text adds to and complements this prior work by addressing the central tenets of the public health approach to the opioid crisis.

The Age of Fentanyl

The Age of Fentanyl
  • Author : Brodie Ramin
  • Publisher :Unknown
  • Release Date :2020-03-14
  • Total pages :232
  • ISBN : 9781459746725
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Summary : Is there a way to end North America’s opioid epidemic? In The Age of Fentanyl, Brodie Ramin tells the story of the opioid crisis, showing us the disease and cure from his perspective as an addiction doctor working on the front lines. We meet his patients, hear from other addiction experts, and learn about the science and medicine of opioid addiction and its treatments. He shows us how addiction can be prevented, how knowledge can reduce stigma, and how epidemics can be beaten. Dr. Ramin brings the hopeful message that just as patients and health care workers rallied together to fight HIV one generation ago, a coalition of patients, advocates, scientists, doctors, and nurses is once again finding solutions and making plans to stem the overdose deaths, block the spread of fentanyl, and end the epidemic.

Fighting for Space

Fighting for Space
  • Author : Travis Lupick
  • Publisher :Unknown
  • Release Date :2018-06-05
  • Total pages :407
  • ISBN : 9781551527130
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Summary : North America is in the grips of a drug epidemic; with the introduction of fentanyl, the chances of a fatal overdose are greater than ever, prompting many to rethink the war on drugs. Public opinion has slowly begun to turn against prohibition, and policy-makers are finally beginning to look at addiction as a health issue as opposed to one for the criminal justice system. While deaths across the continent continue to climb, Fighting for Space explains the concept of harm reduction as a crucial component of a city’s response to the drug crisis. It tells the story of a grassroots group of addicts in Vancouver's Downtown Eastside who waged a political street fight for two decades to transform how the city treats its most marginalized citizens. Over the past twenty-five years, this group of residents from Canada's poorest neighborhood organized themselves in response to the growing number of overdose deaths and demanded that addicts be given the same rights as any other citizen; against all odds, they eventually won. But just as their battle came to an end, fentanyl arrived and opioid deaths across North America reached an all-time high. The "genocide" in Vancouver finally sparked government action. Twenty years later, as the same pattern plays out in other cities, there is much that advocates for reform can learn from Vancouver's experience. Fighting for Space tells that story—including case studies in Ohio, Florida, New York, California, Massachusetts, and Washington state—with the same passionate fervor as the activists whose tireless work gave dignity to addicts and saved countless lives.

Pain Management for People with Serious Illness in the Context of the Opioid Use Disorder Epidemic

Pain Management for People with Serious Illness in the Context of the Opioid Use Disorder Epidemic
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Board on Health Care Services,Roundtable on Quality Care for People with Serious Illness
  • Publisher :Unknown
  • Release Date :2019-08-01
  • Total pages :104
  • ISBN : 9780309492232
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Summary : The United States is facing an opioid use disorder epidemic with opioid overdoses killing 47,000 people in the U.S. in 2017. The past three decades have witnessed a significant increase in the prescribing of opioids for pain, based on the belief that patients were being undertreated for their pain, coupled with a widespread misunderstanding of the addictive properties of opioids. This increase in prescribing of opioids also saw a parallel increase in addiction and overdose. In an effort to address this ongoing epidemic of opioid misuse, policy and regulatory changes have been enacted that have served to limit the availability of prescription opioids for pain management. Overlooked amid the intense focus on efforts to end the opioid use disorder epidemic is the perspective of clinicians who are experiencing a significant amount of daily tension as opioid regulations and restrictions have limited their ability to treat the pain of their patients facing serious illness. Increased public and clinician scrutiny of opioid use has resulted in patients with serious illness facing stigma and other challenges when filling prescriptions for their pain medications or obtaining the prescription in the first place. Thus clinicians, patients, and their families are caught between the responses to the opioid use disorder epidemic and the need to manage pain related to serious illness. The National Academies of Sciences, Engineering, and Medicine sponsored a workshop on November 29, 2018, to examine these unintended consequences of the responses to the opioid use disorder epidemic for patients, families, communities, and clinicians, and to consider potential policy opportunities to address them. This publication summarizes the presentations and discussions from the workshop.

Deaths of Despair and the Future of Capitalism

Deaths of Despair and the Future of Capitalism
  • Author : Anne Case,Angus Deaton
  • Publisher :Unknown
  • Release Date :2021-03-02
  • Total pages :336
  • ISBN : 9780691217062
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Summary : A New York Times Bestseller A Wall Street Journal Bestseller A New York Times Notable Book of 2020 A New York Times Book Review Editors’ Choice Shortlisted for the Financial Times and McKinsey Business Book of the Year A New Statesman Book to Read From economist Anne Case and Nobel Prize winner Angus Deaton, a groundbreaking account of how the flaws in capitalism are fatal for America's working class Deaths of despair from suicide, drug overdose, and alcoholism are rising dramatically in the United States, claiming hundreds of thousands of American lives. Anne Case and Angus Deaton explain the overwhelming surge in these deaths and shed light on the social and economic forces that are making life harder for the working class. As the college educated become healthier and wealthier, adults without a degree are literally dying from pain and despair. Case and Deaton tie the crisis to the weakening position of labor, the growing power of corporations, and a rapacious health-care sector that redistributes working-class wages into the pockets of the wealthy. This critically important book paints a troubling portrait of the American dream in decline, and provides solutions that can rein in capitalism's excesses and make it work for everyone.

Neuroimmune Circuits, Drugs of Abuse, and Infectious Diseases

Neuroimmune Circuits, Drugs of Abuse, and Infectious Diseases
  • Author : Herman Friedman,Thomas W. Klein,John J. Madden
  • Publisher :Unknown
  • Release Date :2006-04-11
  • Total pages :274
  • ISBN : 9780306476112
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Summary : Introduction and Perspectives This volume is based on the proceedings of the 7th annual symposium on the topic Neuroimmune Circuits, Infectious Diseases and Drugs of Abuse, Bethesda, Maryland, Oc- ber 7–9, 1999. This symposium, as in the past, focused on newer knowledge concerning the relationship between the immune and nervous systems with regards to the effects of drugs of abuse and infections, including AIDS, caused by the immunodeficiency virus. Presentations discussed the brain-immune axis from the viewpoint of drugs of abuse rather than from the subject of the brain or immunity alone. The major aim of this series of conferences has been to clarify the consequences of immunomodulation induced by drugs of abuse in regards to susceptibility and pathogenesis of infectious diseases, both in man and in various animal model systems. The recreational use of drugs of abuse such as morphine, cocaine, and marijuana by large numbers of individuals in this country and around the world has continued to arouse serious concerns about the consequences of use of such drugs, especially on the normal physiological responses of an individual, including immune responses. Much of the recent data accumulated by investigators show that drugs of abuse, especially opioids and cannabinoids, markedly alter immune responses in human populations as well as in experimental animals, both in vivo and in vitro.