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Therapeutic Strategies in Cancer Biology and Pathology

Therapeutic Strategies in Cancer Biology and Pathology
  • Author : Gajanan V. Sherbet
  • Publisher :Unknown
  • Release Date :2013-07-26
  • Total pages :310
  • ISBN : 9780124165908
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Summary : Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and so constitute an essential element in cancer growth and dissemination. The emphasis in this book is on how appropriate these genes are as molecular targets and how practicable are the constituents of their signal transduction systems as potential candidates and how accessible they are to targeted therapy. Written in a straightforward and clear style with background information supporting the new research, this book will be useful for students and researchers in cancer therapies. Identifies molecular targets and their accessibility for therapeutic intervention Provides information on biological features of tumor development and dissemination Background information provided for each topic

Molecular Approach to Cancer Management

Molecular Approach to Cancer Management
  • Author : Gajanan V. Sherbet
  • Publisher :Unknown
  • Release Date :2017-06-15
  • Total pages :352
  • ISBN : 9780128128978
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Summary : Molecular Approach to Cancer Management discusses molecular mechanisms of cancer initiation, growth and secondary spread, emphasizing how this information can be used to devise new modes of treatment of cancer, especially in combatting secondary spread. The book addresses the basic concepts relating to cancer biology, the genetic determinants, and the signal transduction cascades associated with tumor growth, EMT, stem cell maintenance and propagation, and invasion and metastasis. The salient features of the signaling systems that are amenable to targeted manipulation are emphasized to facilitate research and development in the design of novel therapies and for the planning of new trials. This book is the only unique volume with coverage of topics that target therapy. As such, it is a valuable source for cancer researchers, molecular oncologists and members of the biomedical field who are interested in knowing more about molecular approaches to cancer therapy. Covers all relevant topics with a defined aim of targeted therapy Encompasses the basic aspects of cancer invasion and metastasis Discusses signaling systems operating in normal cells and their deregulation in cancer cells Directs attention to the foci in signaling systems that can be targeted with a new and conventional drug-based approach

Cancer Biology and Treatment

Cancer Biology and Treatment
  • Author : Aysha Divan,Janice A. Royds
  • Publisher :Unknown
  • Release Date :2020-03-27
  • Total pages :192
  • ISBN : 9780198813477
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Summary : This primer provides an overview of the complex processes underpinning cancer development and progression along with a summary of cancer treatment strategies, emphasising the development of targeted molecular therapies and the opportunities they provide. It takes a contemporary and integrated approach, encompassing debates on genetics, epigenetics, and cancer addictions, and highlighting the remaining challenges and future research directions to advance the field.

Research Awards Index

Research Awards Index
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1987
  • Total pages :229
  • ISBN : UOM:39015012725779
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Summary :

Ovarian Cancer

Ovarian Cancer
  • Author : Omer Devaja,Andreas Papadopoulos
  • Publisher :Unknown
  • Release Date :2018-10-24
  • Total pages :364
  • ISBN : 9781789843330
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Summary : Ovarian cancer management is a rapidly changing field with new treatment agents available as a result of a greater understanding of the pathogenesis of this disease. In addition, both surgical and chemotherapeutic treatment strategies are evolving to maximise response in this disease. This book brings together leading specialists from around the world to discuss and outline a variety of new concepts in ovarian cancer, ranging from molecular biology and genetics through screening to both surgical and chemotherapeutic management.

Cancer

Cancer
  • Author : Gary S. Stein,Kimberly P. Luebbers
  • Publisher :Unknown
  • Release Date :2019-07-09
  • Total pages :680
  • ISBN : 9781118962909
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Summary : A guide to recent insights into the genetic and epigenetic parameters of cancer biology and pathology and emerging clinical applications The thoroughly updated second edition of The Biology and Treatment of Cancer, now titled Cancer: Prevention, Early Detection, Treatment and Recovery, goes beyond reviewing the fundamental properties of cancer biology and the relevant issues associated with treatment of the disease. The new edition contains coverage of additional "patient centric" topics and presents cancer biology with selection of topics, facts, and perspectives written in easy-to-understand terms. With contributions from noted experts, the book explores recent advances in the understanding of cancer including breakthroughs in the molecular and cellular basis of cancer and provides strategies for approaching cancer prevention, early detection, and treatment. The authors incorporate recent information on the genetic and epigenetic parameters of cancer biology and pathology with indications of emerging clinical applications. The text offers a unique guide to cancer prevention, early detection, treatment, and recovery for students, caregivers, and most importantly cancer patients. This significant book: Incorporates current insight into the genetic and epigenetic parameters of cancer biology and pathology and information on emerging clinical applications Contains contributions from leaders in cancer research, care, and clinical trials Offers an accessible guide to an accurate and balanced understanding of cancer and the cancer patient Focuses on the importance of cancer prevention, early detection, treatment, and survivorship Written for medical students, students of cancer biology, and caregivers and cancer patients, Cancer: Prevention, Early Detection, Treatment and Recovery offers an authoritative overview of the challenges and opportunities associated with cancer biology, cancer research, and the spectrum of clinical considerations.

Biomedical Index to PHS-supported Research

Biomedical Index to PHS-supported Research
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1994
  • Total pages :229
  • ISBN : MINN:31951P003778522
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Summary :

Journal of the National Cancer Institute

Journal of the National Cancer Institute
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2001
  • Total pages :229
  • ISBN : UCR:31210015805755
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Summary :

Molecular Pathology of Early Cancer

Molecular Pathology of Early Cancer
  • Author : Sudhir Srivastava,Donald Earl Henson,Adi F. Gazdar
  • Publisher :Unknown
  • Release Date :1999
  • Total pages :481
  • ISBN : 9051993730
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Summary : This book describes the principles and the application of the existing molecular methodology for the detection of early cancer. Discussion focuses on the molecular changes characterizing preneoplastic lesions; molecular targets for early detection; validation of molecular targets; and new diagnostic technology for early detection. The advantages of molecular detection over current methods are examined, as well as the importance of identifying and characterizing preneoplastic lesions. In addition to the uses of highly specific molecular probes to detect early cancer, this book demonstrates the many ways in which molecular markers serve oncology. While meeting pressing needs in the practice of medicine, molecular detection of early cancer scientifically necessitates a confrontation with the biology of cancer, such as the genetic determinants of progression, regression, dormancy, and invasion. This work not only discusses the diagnostic value of these molecular methods but views their practical benefits against a background of conventional morphology.

Cancer Research

Cancer Research
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1996
  • Total pages :229
  • ISBN : NWU:35558003504608
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Summary :

Prostate Cancer

Prostate Cancer
  • Author : Leland W. K. Chung,William B. Isaacs,Jonathan W. Simons
  • Publisher :Unknown
  • Release Date :2007-11-10
  • Total pages :508
  • ISBN : 9781597452243
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Summary : Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, reviews new, valuable approaches to the treatment of prostate cancer in men. The latest edition contains new material on molecular imaging, new treatments for prostate cancer, molecular targets, cell signaling pathways, bioinformatics, and pathogenomics. The book details the latest innovations and advances in prostate cancer and may be used as a rapid reference text for readers. The volume profiles the latest advances in cancer research and treatment and includes profound studies in prostate stem cells, cancer-host interactions, hedgehog signaling in development and cancer, cholesterol and cell signaling, gene therapy for advanced prostate cancer, and noninvasive strategies such as molecular imaging to visualize gene expression. This new edition also investigates expression profiling and somatic alterations in prostate cancer progression and linkage studies of prostate cancer families to identify susceptibility genes. The issues of racial differences in prostate cancer mortality, radiotherapy for the treatment of locally advanced prostate cancer, recombinant antibody candidates for treatment, taxane-based chemotherapy, lethal phenotypes, and novel and efficient translation clinical trials are also presented in great depth. Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, provides readers with a general reference for prostate cancer from prevention to therapy and will be of value to clinicians, scientists, and administrators who strive to solve the cancer problem.

A Concise Review of Molecular Pathology of Breast Cancer

A Concise Review of Molecular Pathology of Breast Cancer
  • Author : Mehmet Gunduz
  • Publisher :Unknown
  • Release Date :2015-03-25
  • Total pages :234
  • ISBN : 9789535120308
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Summary : Cancer is one of the leading causes of death in most countries and its consequences result in huge economic, social and psychological burden. Breast cancer is the most frequently diagnosed cancer type and the leading cause of cancer death among females. In this book, we discussed gene expression and DNA abnormalities including methylation in breast cancer. A recent important topic, roles of miRNAs and their potential use in cancer therapy have been discussed in this cancer type as well. Bioinformatics is very important part of recent human genome developments and data mining and thus this topic has also been added for the readers. It is hoped that this book will contribute to development of novel diagnostic as well as therapeutic approaches, which lead to cure of breast cancer.

Anticancer Research

Anticancer Research
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2008
  • Total pages :229
  • ISBN : UCLA:L0098923741
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Summary :

Artificial Intelligence and Deep Learning in Pathology E-Book

Artificial Intelligence and Deep Learning in Pathology E-Book
  • Author : Stanley Cohen
  • Publisher :Unknown
  • Release Date :2020-06-02
  • Total pages :288
  • ISBN : 9780323675376
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Summary : Recent advances in computational algorithms, along with the advent of whole slide imaging as a platform for embedding artificial intelligence (AI), are transforming pattern recognition and image interpretation for diagnosis and prognosis. Yet most pathologists have just a passing knowledge of data mining, machine learning, and AI, and little exposure to the vast potential of these powerful new tools for medicine in general and pathology in particular. In Artificial Intelligence and Deep Learning in Pathology, Dr. Stanley Cohen covers the nuts and bolts of all aspects of machine learning, up to and including AI, bringing familiarity and understanding to pathologists at all levels of experience. Focuses heavily on applications in medicine, especially pathology, making unfamiliar material accessible and avoiding complex mathematics whenever possible. Covers digital pathology as a platform for primary diagnosis and augmentation via deep learning, whole slide imaging for 2D and 3D analysis, and general principles of image analysis and deep learning. Discusses and explains recent accomplishments such as algorithms used to diagnose skin cancer from photographs, AI-based platforms developed to identify lesions of the retina, using computer vision to interpret electrocardiograms, identifying mitoses in cancer using learning algorithms vs. signal processing algorithms, and many more.

Angiogenesis

Angiogenesis
  • Author : Michael Klagsbrun,Patricia A. D'Amore
  • Publisher :Unknown
  • Release Date :2012
  • Total pages :522
  • ISBN : 1936113430
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Summary : The generation of the vascular system is an important part of embryonic development. Formation of new blood vessels that supply growing tumors with nutrients is also an essential aspect of cancer progression. Work pioneered by researchers such as Judah Folkman, to whom this book is dedicated, has illuminated the mechanisms by which new blood vessels are produced and the vascular system as a whole is patterned. The contributors to this volume review our understanding of the mechanisms of angiogenesis, its role in cancer and other pathologies, as well as therapeutic approaches that target angiogenesis to combat these diseases.

The Guide to Medical Organizations and Agencies

The Guide to Medical Organizations and Agencies
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2000
  • Total pages :1526
  • ISBN : CORNELL:31924057042263
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Summary :

Proceedings of the American Association for Cancer Research

Proceedings of the American Association for Cancer Research
  • Author : American Association for Cancer Research. Meeting,American Association for Cancer Research
  • Publisher :Unknown
  • Release Date :2001
  • Total pages :229
  • ISBN : NWU:35558004688962
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Summary : Contains abstracts of the scientific proceedings of the 73rd- annual meetings of the American Association for Cancer Research (1982- ).

International Directory of Specialized Cancer Research and Treatment Establishments

International Directory of Specialized Cancer Research and Treatment Establishments
  • Author : International Union against Cancer. Committee on International Collaborative Activities,International Union against Cancer
  • Publisher :Unknown
  • Release Date :1982
  • Total pages :727
  • ISBN : 9290180668
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Summary : Worldwide list of comprehensive cancer centers, cancer research institutes, university departments or biomedical research centers, cancer hospitals, or other hospitals having a multidisciplinary cancer department or unit. Data was collected through a questionnaire, and the directory is as comprehensive as possible. Geographical arrangement by countries. Each entry gives information such as statistics, fields of activity, and personnel. Indexes of establishments, directors, and department heads.

Government Research Directory

Government Research Directory
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2005
  • Total pages :229
  • ISBN : CHI:70674798
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Summary :

Neuroblastoma

Neuroblastoma
  • Author : Swapan K. Ray
  • Publisher :Unknown
  • Release Date :2019-01-11
  • Total pages :334
  • ISBN : 9780128120040
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Summary : Neuroblastoma: Molecular Mechanisms and Therapeutic Interventions comprehensively reviews current concepts in molecular and histopathological mechanisms that influence the growth of human malignant neuroblastoma, along with exciting therapeutic interventions. This book features a broad collection of contributions from leading investigators in histopathology, molecular mechanisms, genetics, epigenetics, microRNAs, proteomics, and metabolism in controlling growth and death in neuroblastoma. Recent developments in therapeutic interventions for neuroblastoma are also covered extensively, including chapters on surgery, chemotherapy, targeted therapy and immunotherapy. This book is ideal for advanced undergraduate students, graduate students, medical students, postdoctoral fellows, and investigators with an interest in current molecular concepts and therapeutic interventions. Comprehensively covers the histopathological characterization, molecular mechanisms, and most recent therapeutic interventions in neuroblastoma Includes recent developments and therapeutic interventions for neuroblastoma, including chapters on surgery, chemotherapy, targeted therapy and immunotherapy Presents a broad scope that provides basic researchers, practitioners and students with the most current overview of recent advances

Research Report

Research Report
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1999
  • Total pages :229
  • ISBN : CHI:58625848
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Summary :