Download Tumor Microenvironment Regulates Tumor Expansion Book PDF

Download full Tumor Microenvironment Regulates Tumor Expansion books PDF, EPUB, Tuebl, Textbook, Mobi or read online Tumor Microenvironment Regulates Tumor Expansion anytime and anywhere on any device. Get free access to the library by create an account, fast download and ads free. We cannot guarantee that every book is in the library.

Handbook of Targeted Cancer Therapy

Handbook of Targeted Cancer Therapy
  • Author : Daniel D. Karp,Gerald S. Falchook
  • Publisher :Unknown
  • Release Date :2014-09-09
  • Total pages :288
  • ISBN : 1469894580
GET BOOK HERE

Summary : Make optimal use of the latest personalized therapeutic strategies with Handbook of Targeted Cancer Therapy! This concise, practical oncology reference examines more than 140 targeted therapy agents for which clinical trial data are available, and explains when and how you can use them to most effectively combat cancer. Approach clinical challenges from any direction with separate sections on Targets by Organ Site, Carcinogenesis from the Perspective of Targeted Therapy, Molecular Targets and Pathways, and Targeted Therapy Agents. Find information easily thanks to a color-coded format and an intuitive organization. Access the complete contents online and on mobile devices, with regular updates to include newly approved treatments. Important state of the art cancer information for caregivers, researchers, other health care professionals, and even patients

Tumor Microenvironment

Tumor Microenvironment
  • Author : Alexander Birbrair
  • Publisher :Unknown
  • Release Date :2020
  • Total pages :229
  • ISBN : 3030355829
GET BOOK HERE

Summary :

Stromal Cells

Stromal Cells
  • Author : Mani T. Valarmathi
  • Publisher :Unknown
  • Release Date :2019-01-23
  • Total pages :260
  • ISBN : 1789849845
GET BOOK HERE

Summary : Stromal cells are connective tissue cells of any organ, and they support the function of the parenchymal cells of that particular organ. Stromal/stromal stem cells are fundamentally a heterogeneous population of cells with contradictory differentiation potential depending upon their environmental niche. Stromal cell biology is not only intriguing, but equally stromal cell ontogeny in vivo remains challenging. In recent years there has been substantial advances in our understanding of stromal cell biology, especially stromal cell isolation, characterization, differentiation, and interactions in physiological (epithelial-stromal interactions) as well as pathophysiological (stromal-cancer interactions) contexts. In addition, stromal cells are also utilized more and more as a therapeutic tool not only in the field of gene therapy but also in the translational field of tissue engineering and regenerative medicine. Therefore, the goal of this book is to consolidate the recent advances in the area of stromal/stromal stem cell biology covering a broad range of interrelated topics in a timely fashion and to disseminate that knowledge in a lucid way to a greater scientific audience. This book will prove highly useful for students, researchers, and clinicians in stem cell biology, developmental biology, cancer biology, pathology, oncology, as well as tissue engineering and regenerative medicine. This quick reference will benefit anyone desiring a thorough overview of stromal cell structure, function, and its therapeutic implications.

Tumor Microenvironment

Tumor Microenvironment
  • Author : Alexander Birbrair
  • Publisher :Unknown
  • Release Date :2020
  • Total pages :108
  • ISBN : 3030366677
GET BOOK HERE

Summary : Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of chemokines in the tumor microenvironment. Each chapter focuses on the chemokines patterns of expression, their regulation, and their roles in immune cell recruitment, as well as how they affect cancer immunity and tumorigenesis. Taken alongside its companion volumes, Tumor Microenvironment: The Role of Chemokines - Part A updates us on what we know about various aspects of the tumor microenvironment as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking a comprehensive update on research in the tumor microenvironment.

Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor

Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor
  • Author : Terry Lichtor
  • Publisher :Unknown
  • Release Date :2015-03-25
  • Total pages :434
  • ISBN : 953512031X
GET BOOK HERE

Summary : A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular, recent new avenues regarding the role of microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to radiation therapy have been developed. A discussion of certain surgical management issues including improvements in imaging along with issues concerning tumor induced epilepsy is included. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge. In this book, a review of the latest information on these topics along with a variety of new therapeutic treatment strategies with an emphasis on molecular targeted therapies is provided.

Physics of Cancer

Physics of Cancer
  • Author : Claudia Mierke
  • Publisher :Unknown
  • Release Date :2018-10-24
  • Total pages :500
  • ISBN : 9780750317511
GET BOOK HERE

Summary : This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.

Tumor Microenvironment and Cellular Stress

Tumor Microenvironment and Cellular Stress
  • Author : Constantinos Koumenis,Ester Hammond,Amato Giaccia
  • Publisher :Unknown
  • Release Date :2013-11-23
  • Total pages :290
  • ISBN : 146145915X
GET BOOK HERE

Summary : The collection of chapters in this proceeding volume reflects the latest research presented at the Aegean meeting on Tumor Microenvironment and Cellular Stress held in Crete in Fall of 2012. The book provides critical insight to how the tumor microenvironment affects tumor metabolism, cell stemness, cell viability, genomic instability and more. Additional topics include identifying common pathways that are potential candidates for therapeutic intervention, which will stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery.

Cancer-Associated Thrombosis

Cancer-Associated Thrombosis
  • Author : Alok A. Khorana,Charles W. Francis
  • Publisher :Unknown
  • Release Date :2007-09-26
  • Total pages :296
  • ISBN : 9781420048001
GET BOOK HERE

Summary : Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides an authoritative discussion of strategies to effectively implement and interpret the new ASCO/NCCN directives. Standing as the only up-to-date source to readily examine exciting new translational science findings regarding the biology of cancer-associated thrombosis, as well as new clinical recommendations, this guide supplies an authoritative and current discussion of the mechanisms, management, and prevention of cancer-associated thrombosis.

Summers And Winters At Balmwhapple: By The North Sea

Summers And Winters At Balmwhapple: By The North Sea
  • Author : Sir John Skelton
  • Publisher :Unknown
  • Release Date :2019-03-27
  • Total pages :272
  • ISBN : 9781011581078
GET BOOK HERE

Summary : This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Oncoimmunology

Oncoimmunology
  • Author : Laurence Zitvogel,Guido Kroemer
  • Publisher :Unknown
  • Release Date :2017-12-13
  • Total pages :724
  • ISBN : 3319624318
GET BOOK HERE

Summary : In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals. Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hope that this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field.

Tumor Microenvironment

Tumor Microenvironment
  • Author : Alexander Birbrair
  • Publisher :Unknown
  • Release Date :2020-02-06
  • Total pages :160
  • ISBN : 3030357279
GET BOOK HERE

Summary : This volume discusses recent research advances in cancer biology, focusing on the role of the tumor microenvironment. Taken alongside its companion volumes, Tumor Microenvironment: Recent Advances covers the latest research on various aspects of the tumor microenvironment, as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists studied the tumor microenvironment as well as how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students, as well as researchers seeking an update on research on the tumor microenvironment.

The Tumor Microenvironment

The Tumor Microenvironment
  • Author : Rebecca G. Bagley
  • Publisher :Unknown
  • Release Date :2010-09-02
  • Total pages :770
  • ISBN : 9781441966155
GET BOOK HERE

Summary : The fact that tumors are composed of both tumor cells and host cells has long been known. These tumor-associated cells include vascular endothelial cells and pe- cytes, as well as inflammatory cells such as neutrophils, monocytes, macrophages, mast cells and eosinophils, and lymphocytes. The tumor cells also interact with stromal cells and with elements of the tissue extracellular matrix. What has been less appreciated is the role that these cells could have in modulating the growth, invasion, and metastasis of the tumor. Early on, the elements of what we now call the tumor microenvironment were considered to be more or less innocent bysta- ers to the role of the tumor cells as they grew and invaded local sites. Today, there is an increased understanding of the critical role of the tumor microenvironment as dramatically influencing the course of tumor development and dissemination. This volume represents a superb compilation of the latest thoughts and data regarding the role of each essential component of the tumor microenvironment in cancer development and progression. Perhaps, the earliest recognition of the role of nonmalignant cells as cancer re- lators was the recognition that lymphocytes can participate in what was termed “immune surveillance” in the 1960s. Our understanding of tumor immunity has improved markedly since then, and there are now successful clinical studies sh- ing the potential use of immune-based therapies in cancer treatment.

Endothelial Biomedicine

Endothelial Biomedicine
  • Author : William C. Aird
  • Publisher :Unknown
  • Release Date :2007-09-03
  • Total pages :229
  • ISBN : 1139465872
GET BOOK HERE

Summary : The endothelium, the cell layer that forms the inner lining of blood vessels, is a spatially distributed system that extends to all areas of the human body. Clinical and basic research demonstrates that the endothelium plays a crucial role in mediating homeostasis and is involved in virtually every disease, either as a primary determinant of pathophysiology or as a victim of collateral damage. The endothelium has remarkable, though largely untapped, diagnostic and therapeutic potential. This volume bridges the bench-to-bedside gap in endothelial biomedicine, advancing research and development and improving human health. The book is the first to systematically integrate knowledge about the endothelium from different organ-specific disciplines, including neurology, pulmonary, cardiology, gastroenterology, rheumatology, infectious disease, hematology-oncology, nephrology, and dermatology. It's interdisciplinary approach, which draws on expertise from such diverse fields as evolutionary biology, comparative biology, molecular and cell biology, mathematical modeling and complexity theory, translational research, and clinical medicine.

Immune Surveillance

Immune Surveillance
  • Author : Richard T. Smith
  • Publisher :Unknown
  • Release Date :2012-12-02
  • Total pages :552
  • ISBN : 0323146260
GET BOOK HERE

Summary : Immune Surveillance deals with the issues regarding tumor immunology and surveillance, in which the central theme is all about the life span of the mammalian host that is depleted by the environment with mutagenic agents and solutions. The book is divided into six chapters. It includes discussions on the organization and modulation of cell membrane receptors, as well as the origin and expression of membrane antigens. It also covers the topics on the triggering mechanisms for and effector mechanisms activated by the cellular recognition. These topics analyze and evaluate alternatives for the recognition and destruction mechanisms in the knowledge of cell cooperation and requirements for immune recognition. A chapter provides discourse on a solution for the paradox of thriving tumors based on the demonstrable in vitro host immunity. Another discusses the generation of antibody diversity and the theory of self-tolerance. The last chapter explains the evaluation of the evidence for immune surveillance. This reference will be invaluable to those who specialize in immunology.

Tumor Microenvironment

Tumor Microenvironment
  • Author : Alexander Birbrair
  • Publisher :Unknown
  • Release Date :2020-04-07
  • Total pages :181
  • ISBN : 3030401464
GET BOOK HERE

Summary : Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on the extracellular matrix components of the tumor during cancer development. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include heparan sulphate, hyaluronan, fibronectin, perlecan, glypican, matrix metalloproteinases, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Extracellular Matrix Components – Part A updates us on what we know about the different aspects of the tumor microenvironment, as well as apprises us on the future advances in the field. For the newest generation of researchers, this volume serves as a useful introduction to the history of scientists’ focus on the tumor microenvironment, and explores how this knowledge is currently applied in cancer treatments. The book is an essential text for advanced cell biology and cancer biology students, as well as for scientists seeking an update on the developments in tumor microenvironment research. All of the chapter authors are renowned international experts in the field of cancer biology, and in the specific subfields that are the focus of their chapters.

Tumor Metastasis

Tumor Metastasis
  • Author : Ke Xu
  • Publisher :Unknown
  • Release Date :2016-09-14
  • Total pages :266
  • ISBN : 953512630X
GET BOOK HERE

Summary :

Central Nervous System Metastases

Central Nervous System Metastases
  • Author : Manmeet Ahluwalia,Philippe Metellus,Riccardo Soffietti
  • Publisher :Unknown
  • Release Date :2019-11-05
  • Total pages :421
  • ISBN : 3030234177
GET BOOK HERE

Summary : This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.

The Extracellular Matrix: an Overview

The Extracellular Matrix: an Overview
  • Author : Robert Mecham
  • Publisher :Unknown
  • Release Date :2011-02-16
  • Total pages :426
  • ISBN : 9783642165559
GET BOOK HERE

Summary : Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

Cell-Extracellular Matrix Interactions in Cancer

Cell-Extracellular Matrix Interactions in Cancer
  • Author : Roy Zent,Ambra Pozzi
  • Publisher :Unknown
  • Release Date :2010-10-22
  • Total pages :314
  • ISBN : 1441908153
GET BOOK HERE

Summary : Cancer was thought to originate from alterations in intercellular signaling that resulted in the transformation of cells, their uncontrolled proliferation and metastasis. There is now an increasing body of evidence demonstrating that the surrounding matrix and cell-matrix interactions are also major players in this process. Cells adhere and receive signals from various extracellular matrices via transmembrane receptors, the best known of which are the heterodimeric glycoproteins, integrins.

Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy

Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy
  • Author : Pawel Kalinski
  • Publisher :Unknown
  • Release Date :2017-12-22
  • Total pages :264
  • ISBN : 331967577X
GET BOOK HERE

Summary : The tumor microenvironment has become a very important and hot topic in cancer research within the past few years. The tumor microenvironment is defined as the normal cells, molecules, and blood vessels that surround and feed a tumor cell. As many scientists have realized, studying the tumor microenvironment has become critical to moving the field forward, since there are many players in a tumor’s localized and surrounding area, which can significantly change cancer cell behavior. There is a dual relationship wherein the tumor can change its microenvironment and the microenvironment can affect how a tumor grows and spreads. Tumor Microenvironment in Cancer Progression and Cancer Therapy aims to shed light on the mechanisms, factors, and mediators that are involved in the cancer cell environment. Recent studies have demonstrated that in addition to promoting tumor progression and protecting tumor cells from the spontaneous immune-mediated rejection and different forms of cancer therapeutics, tumor microenvironment can also be a target and mediator of both standard and newly-emerging forms of cancer therapeutics. Thus, the dual role of the tumor microenvironment is the integral focus of the volume. The volume highlights the bi-directional interactions between tumor cells and non-malignant tumor component during tumor progression and treatment. It also focuses on the three groups of the reactive tumor component: stromal cells, blood vessels and the infiltrating immune cells. These three groups are discussed under the lens of their role in promoting tumor growth, shielding the tumor from rejection and from standard forms of cancer therapies. They are emerging as targets and mediators of standard and new forms of potential therapy.

The Biology of Cancer

The Biology of Cancer
  • Author : Weinberg, Robert A.
  • Publisher :Unknown
  • Release Date :2013-05-24
  • Total pages :28
  • ISBN : 0815345283
GET BOOK HERE

Summary : Incorporating the most important advances in the fast-growing field of cancer biology, the text maintains all of its hallmark features. It is admired by students, instructors, researchers, and clinicians around the world for its clear writing, extensive full-color art program, and numerous pedagogical features.