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Tweak to Transform

Tweak to Transform
  • Author : Mike Hughes
  • Publisher :
  • Release Date :2002-08-01
  • Total pages :264
  • ISBN : 1855391406
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Summary : Improving teaching is the key to genuine and sustainable school improvement. Improvement involves persuading teachers to change and develop their practice but, as anyone who has ever tried will testify, this is far from easy. The focus of Tweak to Transform is what head teachers and school leaders can do to manage the change process and improve the quality of teaching in a school. Essentially, Tweak to Transform is a practical handbook that seeks to address three questions. What do we know about change? What do we know about learning? What do we know about leading and managing the improvement process? While there is no single successful recipe for improving teaching in a school, this book attempts to establish some key principles. The result is a collection of thoughts, activities strategies and models that have been developed and successfully implemented in a wide range of schools. >

Tweak

Tweak
  • Author : Nic Sheff
  • Publisher :
  • Release Date :2012-12-11
  • Total pages :368
  • ISBN : 1471109739
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Summary : THE NEW YORK TIMES BESTSELLER NOW A MAJOR FILM, STARRING STEVE CARELL AND BAFTA AND GOLDEN GLOBE NOMINATED TIMOTHEE CHALAMET ‘It was like being in a car with the gas pedal slammed down to the floor and nothing to do but hold on and pretend to have some semblance of control. But control was something I'd lost a long time ago.’ Nic Sheff was drunk for the first time at age 11. In the years that followed, he would regularly smoke pot, do cocaine and ecstasy, and develop addictions to crystal meth and heroin. Even so, he felt like he would always be able to quit and put his life together whenever he needed to. It took a violent relapse one summer to convince him otherwise. In a voice that is raw and honest, Nic spares no detail in telling us the compelling true story of his relapse and the road to recovery. He paints an extraordinary picture for us of a person at odds with his past, with his family, with his substances, and with himself. Tweak is a raw, harrowing, and ultimately hopeful tale of the road from relapse to recovery and complements his father’s parallel memoir, Beautiful Boy. Praise for Nic Sheff:- ‘Difficult to read and impossible to put down.’Chicago Tribune 'Nic Sheff's wrenching tale is told with electrifying honesty and insight.' Armistead Maupin

Tweak It

Tweak It
  • Author : Cali Williams Yost
  • Publisher :
  • Release Date :2013-01-08
  • Total pages :272
  • ISBN : 1455517860
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Summary : As the demands of work grow more intense, personal life can get shoved to the side. But resolving the job-versus-life conflict doesn't require the kind of big, disruptive, scary transformation that so many time-management "experts" recommend. In TWEAK IT, Cali Williams Yost proves that a comfortable work+life fit can be achieved through making small, consistent, everyday changes--tweaks--that, cumulatively, will optimize job performance and well-being. This engaging, practical book, filled with case studies of people who've tweaked their way to professional success and personal satisfaction, guides readers through an easy-to-implement program that can be tailored to suit any individual's life, both on off the job.

Regulation of Tissue Responses: The TWEAK/Fn14 Pathway and other TNF/ TNFR Superfamily Members that Activate Noncanonical NFkB Signaling

Regulation of Tissue Responses: The TWEAK/Fn14 Pathway and other TNF/ TNFR Superfamily Members that Activate Noncanonical NFkB Signaling
  • Author : Linda C. Burkly,Timothy S. Zheng,John Silke
  • Publisher :
  • Release Date :2016-01-21
  • Total pages :329
  • ISBN : 288919700X
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Summary : The immune system mediates tissue responses under both physiological and pathological conditions, impacting the inflammatory, fibrogenic and regenerative components. In addition to various leukocyte subsets, it is now recognized that epithelial, endothelial and other non-hematopoietic tissue cell types actively contribute to the interplay shaping tissue responses. Further understanding the molecular pathways and mechanisms mediating these tissue responses is of great interest. In the past decade, TNF-like weak inducer of apoptosis (TWEAK) and its receptor, FGF-inducible molecule-14 (Fn14), members of the TNF/TNFR superfamily, have emerged as a prominent molecular axis regulating tissue responses. Generally leukocyte-derived, TWEAK signals through Fn14 which is highly induced in injured and diseased tissues on the surface of parenchymal, stromal and progenitor cells, thereby orchestrating a host of tissue-shaping responses, including inflammation, angiogenesis, cell proliferation or death, and the regulation of progenitor cells. Compelling preclinical results indicate that whereas transient TWEAK/Fn14 activation promotes productive tissue responses after acute injury, excessive or persistent TWEAK/Fn14 activation drives pathological tissue responses, leading to progressive damage and degeneration in target organs of injury, autoimmune and inflammatory diseases and cancer. Given that the highly inducible pattern of Fn14 expression is well conserved between mouse and man, the role of TWEAK/Fn14 in human disease is an area of intense investigation. Recent findings have also begun to shed light on how the TWEAK/Fn14 pathway fits into the immune network, interplaying with other well-established pathways, including TNFa, IL-17, IL-13 and TGFb, in regulating tissue responses. The noncanonical nuclear factor kB (NF?B) pathway plays a role in immunity and disease pathologies and appears to be activated by only a subset of TNF/ TNFR superfamily members. Of the various signaling pathways downstream of TWEAK/Fn14, particular attention has been placed on the noncanonical NF?B pathway given that given that TWEAK induces acute activation of canonical NF?B but prolonged activation of noncanonical pathway. Thus dovetailing of the TWEAK/Fn14 axis with noncanonical NF?B pathway activation may be a key mechanism underlying tissue responses. Also of great interest is a deeper understanding of where, when and how tissue responses are regulated by other TNF/ TNFR superfamily members that can signal through noncanonical NF?B. This Research Topic issue will cover: 1. TWEAK/Fn14 pathway biology, role in tissue responses, injury, and disease pathogenesis 2. Role of noncanonical NFkB signaling cascade in tissue responses 3. Translational studies of relevance of TWEAK/Fn14 and noncanonical NFkB in human disease 4. Other TNF superfamily members’ signaling through noncanonical NFkB in the regulation of tissue responses 5. Reviews and Perspectives on the above

Tweak it! Second Ed.

Tweak it! Second Ed.
  • Author : Edward Caplan
  • Publisher :
  • Release Date :
  • Total pages :329
  • ISBN : 1300685700
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Summary :

Tweak Tweak

Tweak Tweak
  • Author : Eve Bunting
  • Publisher :
  • Release Date :2011-05-23
  • Total pages :40
  • ISBN : 0547573634
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Summary : Little Elephant and Mama Elephant are going for a walk. “Hold on to my tail,” says Mama. “If you want to ask me a question, tweak twice.” Tweak, tweak! “Mama, what is that?” Little Elephant is curious about the frog, the monkey, the songbird, the butterfly, and the crocodile—and especially about what a little elephant can do. Mama knows just how to answer, to help her cherished Little Elephant grow. Eve Bunting’s tender text and Sergio Ruzzier’s whimsical illustrations make this walk with Mama an excursion any little elephant would enjoy.

Space Tweak

Space Tweak
  • Author : Turk Allcott
  • Publisher :
  • Release Date :2012
  • Total pages :329
  • ISBN : 1300130334
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Summary :

Tweak Your Flash

Tweak Your Flash
  • Author : Thomas E. Beames, Jr.
  • Publisher :
  • Release Date :2012-05-07
  • Total pages :133
  • ISBN : 1469190990
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Summary : You want a different perspective on old ideas. Youre open to a new way of thinking about your business, and youd like to be creatively provoked. Perhaps youve hit a roadblock in your communications, or you want something entertaining but relevant to help you see your career through another lens. Tweak Your Flash is simply about perspective; viewing your surroundings from a different angle will uncover nuances that otherwise go unnoticed. Looking at how a bird approaches a landing, or why a day with a favorite uncle holds such fond memories, can be applied to your professional life and make you more effective and fulfilled in your work. This is a book to be read and used over time; keep it handy, and reference it every now and then. Accepting for a moment that youre not as good at your job as youll ever be, use these ideas to ensure youre flashing the right message, at the right frequency, to the right people.

Tweak It and Freak It

Tweak It and Freak It
  • Author : Paul McFedries
  • Publisher :
  • Release Date :2009-03-27
  • Total pages :480
  • ISBN : 9780768686715
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Summary : Tweak It and Freak It A Killer Guide to Making Windows Run Your Way Hundreds of millions of people use Windows every day, and it’s a safe bet that some of them would not describe themselves as happy campers. Regardless of skill level, most people have something they dislike about Windows, and they often have a whole laundry list of Windows gripes. “Why can’t Windows do this rather than that?” “Why does Windows do X instead of Y?” “Wouldn’t it be great if Windows could do Z?” Most people think Windows is set in stone, but it isn’t! Strip off that veneer and a whole world comes into view, one that’s hackable, moddable, tweakable, customizable, and personalizable. This book shows you the tools and technologies that anyone can use to hack almost every aspect of Windows, from startup to shutdown, from the interface to the Internet, from security to scripting. • Speed up your tired PC with a fistful of easy-to-do, but oh so powerful tweaks! • Tired of looking at the same old Windows day in and day out? So are we! That’s why we show you how to give Windows a makeover! • Want to be more productive at work or home? This book is full of productivity tweaks that not only make Windows more fun to use, but also save you tons of time. • Create custom backup routines that safeguard your precious data. • Tighten the security of your PC and your network to stop would-be thieves in their tracks. • Dual-boot Windows XP and Vista on the same machine, or dare we say it, run MacOS on your PC! We won’t tell. Paul McFedries is a passionate computer tinkerer and Windows expert. He is the author of more than 60 computer books that have sold more than 3 million copies worldwide. His recent titles include the Sams Publishing books Windows Vista Unleashed, Second Edition, and Windows Home Server Unleashed, and the Que Publishing books Build It. Fix It. Own It. : Networking with Windows Vista, Formulas and Functions with Microsoft Excel 2007, Tricks of the Microsoft Office 2007 Gurus, and Microsoft Access 2007 Forms, Reports, and Queries. Paul is also the proprietor of Word Spy (www.wordspy.com), a website devoted to tracking new words and phrases as they enter the English language. CATEGORY: Windows Operating System COVERS: Windows Vista and XP USER LEVEL: Beginning-Intermediate

Tweak a Dragon's Tail

Tweak a Dragon's Tail
  • Author : John Graham
  • Publisher :
  • Release Date :2008-03-21
  • Total pages :296
  • ISBN : 1434897540
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Summary : This is an adventure story set in the People's Republic of China in the early eighties before the nation was opened to the Western world. An engineer, Toby, from Hong Kong follows his mentally disturbed brother who has entered China. He fears the worst: illegal entry without a passport to be sure but perhaps also an act against China itself. Toby's colleague, Donna, his lover, helps in his quest while a mysterious college student, Kathy, invades the scene. The path leads deep into China. The story is a vivid picture of what the country and its people were like in the seventies: full of intrigue under a totalitarian regime. Guangzhou, Guilin, the Yangtze, and Chongking lead to Beijing and a triple-whammy ending.

Tales from the Tweak Side

Tales from the Tweak Side
  • Author : Michael Lites
  • Publisher :
  • Release Date :2006-07-01
  • Total pages :196
  • ISBN : 1847281729
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Summary : Based on the true story of a San Francisco durg dealer in the 90's. This book reads like a roller coaster ride. It's fun, it's raw and it's very real. It's probably one of the best and only books out there about what it's really like to get swept up into the world of meth.

Death Receptors and Cognate Ligands in Cancer

Death Receptors and Cognate Ligands in Cancer
  • Author : Holger Kalthoff
  • Publisher :
  • Release Date :2010-03-12
  • Total pages :280
  • ISBN : 9783642030451
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Summary : Death receptors play a central role in directing apoptosis in mammalian cells. This process of active cell death is important for a number of biological processes, e.g. for the regulation of the immune system. Death receptors are cell surface receptors that transmit apoptotic signals initiated by corresponding death ligands. Many complex signaling pathways are activated and apoptosis is the final result of a complex biochemical cascade of events. Besides their role in the induction of cell death, evidence now exists that death receptors are able to activate several non-apoptotic signaling pathways which, depending on cellular context, may lead to apoptosis resistance, secretion of pro-inflammatory proteins, proliferation and invasive growth of cancer cells. This book looks at the molecular basis of death receptor signaling and the role of death receptors in cancer development.

Tweak the Devil's Nose

Tweak the Devil's Nose
  • Author : Richard Deming
  • Publisher :
  • Release Date :1953
  • Total pages :250
  • ISBN :
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Summary :

Tweak and the Absolutely Right Whale

Tweak and the Absolutely Right Whale
  • Author : Patricia Bell Dubin
  • Publisher :
  • Release Date :1993-12
  • Total pages :48
  • ISBN : 9781880812068
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Summary :

Intercellular Signaling Peptides and Proteins—Advances in Research and Application: 2012 Edition

Intercellular Signaling Peptides and Proteins—Advances in Research and Application: 2012 Edition
  • Author : N.A
  • Publisher :
  • Release Date :2012-12-26
  • Total pages :841
  • ISBN : 1464991383
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Summary : Intercellular Signaling Peptides and Proteins—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Intercellular Signaling Peptides and Pr. The editors have built Intercellular Signaling Peptides and Proteins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Intercellular Signaling Peptides and Pr in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Intercellular Signaling Peptides and Proteins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Selected Areas in Cryptography

Selected Areas in Cryptography
  • Author : Eli Biham
  • Publisher :
  • Release Date :2007-09-21
  • Total pages :395
  • ISBN : 3540744614
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Summary : This book constitutes the thoroughly refereed post-proceedings of the 13th International Workshop on Selected Areas in Cryptography, SAC 2006, held in Montreal, Canada in August 2006. The 25 revised full papers presented together with 2 invited talks were carefully reviewed and selected from 86 submissions. The papers are organized in topical sections on block cipher cryptanalysis, stream cipher cryptanalysis, block and stream ciphers, side-channel attacks, efficient implementations, message authentication codes, and hash functions.

Heart Failure: A Companion to Braunwald's Heart Disease E-book

Heart Failure: A Companion to Braunwald's Heart Disease E-book
  • Author : Douglas L. Mann
  • Publisher :
  • Release Date :2010-11-11
  • Total pages :928
  • ISBN : 1437703631
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Summary : Dr. Douglas L. Mann, one of the foremost experts in the field, presents the 2nd Edition of Heart Failure: A Companion to Braunwald’s Heart Disease. This completely reworked edition covers the scientific and clinical guidance you need to effectively manage your patients and captures the dramatic advances made in the field over the last five years. Now in full color, this edition features eleven new chapters, including advanced cardiac imaging techniques, use of biomarkers, cell-based therapies and tissue engineering, device therapies, and much more. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Use this Braunwald’s companion as the definitive source to prepare for the ABIM’s new Heart Failure board exam. Access the fully searchable contents of the book online at Expert Consult. This edition includes 67 new authors, who are experts in the field of heart failure Stay on the cutting edge with new chapters on: The latest practice guidelines for medical and device therapy Hemodynamic assessment of heart failure Contemporary medical therapy for heart failure patients with reduced and preserved ejection fraction Biomarkers in heart failure Pulmonary hypertension Management of co-morbidities in heart failure Mechanical cardiac support devices Get up to speed with the latest clinical trials, as well as how they have influenced current practice guidelines Explore what’s changing in key areas such as basic mechanisms of heart failure, genetic screening, cell and gene therapies, pulmonary hypertension, heart failure prevention, co-morbid conditions, telemedicine/remote monitoring, and palliative care

Mastering Autodesk Inventor 2010

Mastering Autodesk Inventor 2010
  • Author : Curtis Waguespack
  • Publisher :
  • Release Date :2010-12-28
  • Total pages :816
  • ISBN : 9781118058701
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Summary : A complete tutorial for the real-world application of Autodesk Inventor, plus video instruction on DVD Used to design everything from airplanes to appliances, Autodesk Inventor is the industry-leading 3D mechanical design software. This detailed tutorial and reference covers practical applications to help you solve design problems in your own work environment, allowing you to do more with less. It also addresses topics that are often omitted from other guides, such as Inventor Professional modules, design tactics for large assemblies, using 2D and 3D data from other CAD systems, and a detailed overview of the Inventor utility tools such as Design Assistant and Task Scheduler that you didn't even know you had. Teaches the most popular 3D mechanical design software in the context of real-world workflows and work environments Provides an overview of the Inventor 2010 ribbon Interface, Inventor design concepts, and advanced information on productivity-boosting and visualization tools Offers crucial information on data exchange, including SolidWorks, Catia, Pro-E, and others. Shares details on documentation, including exploded presentation files, simple animations, rendered animations and stills with Inventor Studio, and sheet metal flat patterns Covers Inventor, Inventor Professional, and Inventor LT Includes a DVD with before-and-after tutorial files, a searchable PDF of the book, innovative video tutorials for each chapter, and more Mastering Autodesk Inventor teaches you to get the most from the software and provides a reference to help you on the job, allowing you to utilize the tools you didn't even know you had to quickly achieve professional results. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.

IPad 3 Secrets

IPad 3 Secrets
  • Author : Don Gall
  • Publisher :
  • Release Date :2013-02-08
  • Total pages :34
  • ISBN : 1482384329
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Summary : If you are an individual that loves the products from Apple then you will be more than intrigued by the iPad 3. Of course upon receiving you will want to know just how much you can get done with it. you will want to go through all the features and know what apps you can get on the device. This is where “IPad 3 Secrets: How To Get The Most From Your IPad” fits in. it is a book written by a self proclaimed techie that has all the information that you could ever need to get even more great features on your new iPad. The author leaves the reader to make the decision as to whether or not they want to jailbreak their device as not everyone is able to do so correctly or deal with the challenges that can come up if something goes wrong. Everything is presented in sequential order and can quickly be read and understood by all, even the person in the room without much technological knowledge. The aim of this guide is to provide the most current information possible about the iPad 3 and how one can get the most out of the device.

Creating a Digital Home Entertainment System with Windows Media Center

Creating a Digital Home Entertainment System with Windows Media Center
  • Author : Michael The Green Button,Button,Michael R. Miller
  • Publisher :
  • Release Date :2006-04-21
  • Total pages :408
  • ISBN : 9780132713177
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Summary : Even though the Windows Media Center interface is simple to operate, not all activities are intuitive or easy to implement. You may need help determining which type of Media Center PC to buy, or with connecting and configuring the Media Center PC in your home theater system. Creating a Digital Home Entertainment System with Windows Media Center book brings the experience and expertise of The Green Button (the premiere Media Center website) and author Michael Miller to help you plan, use, and troubleshoot your new Media Center PCs and get the most out of Windows Media Center Edition.

Obesity and Diabetes: New Insights for the Healthcare Professional: 2011 Edition

Obesity and Diabetes: New Insights for the Healthcare Professional: 2011 Edition
  • Author : N.A
  • Publisher :
  • Release Date :2012-01-09
  • Total pages :313
  • ISBN : 1464900507
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Summary : Obesity and Diabetes: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Obesity and Diabetes. The editors have built Obesity and Diabetes: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Obesity and Diabetes in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Obesity and Diabetes: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.