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Ultrasmall Lanthanide Oxide Nanoparticles for Biomedical Imaging and Therapy

Ultrasmall Lanthanide Oxide Nanoparticles for Biomedical Imaging and Therapy
  • Author : Gang Ho Lee,Jeong-Tae Kim
  • Publisher :Unknown
  • Release Date :2014-11-22
  • Total pages :208
  • ISBN : 9780081000694
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Summary : Most books discuss general and broad topics regarding molecular imagings. However, Ultrasmall Lanthanide Oxide Nanoparticles for Biomedical Imaging and Therapy, will mainly focus on lanthanide oxide nanoparticles for molecular imaging and therapeutics. Multi-modal imaging capabilities will discussed, along with up-converting FI by using lanthanide oxide nanoparticles. The synthesis will cover polyol synthesis of lanthanide oxide nanoparticles, Surface coatings with biocompatible and hydrophilic ligands will be discussed and TEM images and dynamic light scattering (DLS) patterns will be provided. Various techniques which are generally used in analyzing the synthesized surface coated nanoparticles will be explored and this section will also cover FT­, IR analysis, XRD analysis, SQUID analysis, cytotoxicity measurements and proton relaxivity measurements. In vivo MR images, CT images, fluorescence images will be provided and Therapeutic application of gadolinium oxide nanoparticles will be discussed. Finally, future perpectives will be discussed. That is, present status and future works needed for clinical applications of lanthanide oxide nanoparticles to molecular imagings will be discussed. Synthesis will be discussed in detail General characterizations of nanoparticles before in vivo applications will be discussed The book will cover all possible applications of lanthanide oxide nanoparticles to molecular imagings such as MRI, CT, FI as well as therapeutics

Noble Metal-Metal Oxide Hybrid Nanoparticles

Noble Metal-Metal Oxide Hybrid Nanoparticles
  • Author : Satyabrata Mohapatra,Tuan Anh Nguyen,Phuong Nguyen-Tri
  • Publisher :Unknown
  • Release Date :2018-10-11
  • Total pages :674
  • ISBN : 9780128141359
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Summary : Noble Metal-Metal Oxide Hybrid Nanoparticles: Fundamentals and Applications sets out concepts and emerging applications of hybrid nanoparticles in biomedicine, antibacterial, energy storage and electronics. The hybridization of noble metals (Gold, Silver, Palladium and Platinum) with metal-oxide nanoparticles exhibits superior features when compared to individual nanoparticles. In some cases, metal oxides act as semiconductors, such as nano zinc oxide or titanium oxide nanoparticles, where their hybridization with silver nanoparticles, enhanced significantly their photocatalytic efficiency. The book highlights how such nanomaterials are used for practical applications. Examines the properties of metal-metal oxide hybrid nanoparticles that make them so adaptable Explores the mechanisms by which nanoparticles interact with each other, showing how these can be exploited for practical applications Shows how metal oxide hybrid nanomaterials are used in a range of industry sectors, including energy, the environment and healthcare

Design and Applications of Nanoparticles in Biomedical Imaging

Design and Applications of Nanoparticles in Biomedical Imaging
  • Author : Jeff W.M. Bulte,Michel M.J. Modo
  • Publisher :Unknown
  • Release Date :2016-11-25
  • Total pages :469
  • ISBN : 9783319421698
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Summary : This book covers the most recent advances in using nanoparticles for biomedical imaging, including magnetic resonance imaging (MRI), magnetic particle imaging (MPI), nuclear medicine, ultrasound (US) imaging, computed tomography (CT), and optical imaging. Topics include nanoparticles for MRI and MPI, siRNA delivery, theranostic nanoparticles for PET imaging of drug delivery, US nanoparticles for imaging drug delivery, inorganic nanoparticles for targeted CT imaging, and quantum dots for optical imaging. This book serves as a valuable resource for the fundamental science of diagnostic nanoparticles and their interactions with biological targets, providing a practical handbook for improved detection of disease and its clinical implementation.

Nanomaterial - Based Biomedical Applications in Molecular Imaging, Diagnostics and Therapy

Nanomaterial - Based Biomedical Applications in Molecular Imaging, Diagnostics and Therapy
  • Author : Amitabha Acharya
  • Publisher :Unknown
  • Release Date :2020-05-23
  • Total pages :203
  • ISBN : 9789811542800
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Summary : This book comprehensively reviews the recent advances in nanomaterial-based molecular imaging, diagnostics, and personalized therapy. It discusses the novel biocompatible fluorescent nanomaterials, their synthesis, and modern state of art characterization, as well as the various strategies for immobilization of biomacromolecules on the nanomaterial surface and approaches for increasing their stability. In addition, the book describes the synthesis of lectin nanoconjugates using different types of biocompatible raw materials and their systematic characterization. Lastly, it presents our current understanding of the biomolecular carona, which affects nanoparticle-based targeted drug delivery, and examines the conceptual approaches to improve the in-vivo efficacy of targeted drug delivery.

Therapeutic and Diagnostic Nanomaterials

Therapeutic and Diagnostic Nanomaterials
  • Author : Devasena T
  • Publisher :Unknown
  • Release Date :2016-07-19
  • Total pages :109
  • ISBN : 9789811009235
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Summary : This brief highlights nanoparticles used in the diagnosis and treatment of prominent diseases and toxic conditions. Ecofriendly methods which are ideal for the synthesis of medicinally valued nanoparticles are explained and the characteristic features of these particles projected. The role of these particles in the therapeutic field, and the induced biological changes in some diseases are discussed. The main focus is on inflammation, oxidative stress and cellular membrane integrity alterations. The effect of nanoparticles on these changes produced by various agents are highlighted using in vitro and in vivo models. The mechanism of nanoparticles in ameliorating the biological changes is supported by relevant images and data. Finally, the brief demonstrates recent developments on the use of nanoparticles in diagnosis or sensing of some biological materials and biologically hazardous environmental materials.

Radiopharmaceutical Chemistry

Radiopharmaceutical Chemistry
  • Author : Jason S. Lewis,Albert D. Windhorst,Brian M. Zeglis
  • Publisher :Unknown
  • Release Date :2019-04-02
  • Total pages :651
  • ISBN : 9783319989471
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Summary : This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic. The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like “The Production of Radionuclides” and “Basics of Radiochemistry”. The second section is the main focus of the book. In this section, each chapter’s author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a “Best of the Rest” chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including “Bioconjugation Methods,” “Click Chemistry in Radiochemistry”, and “Radiochemical Instrumentation.” This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.

Reactive Species Detection in Biology

Reactive Species Detection in Biology
  • Author : Frederick A. Villamena
  • Publisher :Unknown
  • Release Date :2016-10-23
  • Total pages :340
  • ISBN : 9780124200807
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Summary : Reactive Species Detection in Biology: From Fluorescence to Electron Paramagnetic Resonance Spectroscopy discusses the reactive oxygen species that have been implicated in the pathogenesis of various diseases, presenting theories, chemistries, methodologies, and various applications for the detection of reactive species in biological systems, both in-vitro and in-vivo. Techniques covered include fluorescence, high performance chromatography, mass spectrometry, immunochemistry, and electron paramagnetic resonance spectroscopy. Probe design and development are also reviewed in order to advance new approaches in radical detection through synthesis, computations, or experimental applications. Reviews all current advances in radical detection Emphasizes chemical structures and reaction schemes fundamental to radical detection and identification Describes the uses, advantages, and disadvantages of various probe designs Examines new approaches to radical probe development

Upconverting Nanomaterials

Upconverting Nanomaterials
  • Author : Claudia Altavilla
  • Publisher :Unknown
  • Release Date :2016-10-03
  • Total pages :369
  • ISBN : 9781315354309
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Summary : Upconverting Nanomaterials: Perspectives, Synthesis, and Applications serves as a powerful instrument that explores cutting-edge research knowledge on the topic of upconverting nanosystems, while simultaneously providing the necessary fundamental background for nonspecialist readers. The various aspects of upconverting materials are approached both from a theoretical point of view, particularly upconverting phenomenon, and a practical one. By presenting synthetic strategies, functionalization, production of core shell structures and nanocomposites, this book supplies PhD students, researchers, and scientists with a wealth of ideas they can apply to different fields of research. Thirty-five renowned scientists from around the world have collaborated to produce 11 chapters that help to "make a voyage" through the most important aspects of UPNPs, including syntheses, mechanism, functionalization, and applications.

Near Infrared-Emitting Nanoparticles for Biomedical Applications

Near Infrared-Emitting Nanoparticles for Biomedical Applications
  • Author : Antonio Benayas,Eva Hemmer,Guosong Hong,Daniel Jaque
  • Publisher :Unknown
  • Release Date :2020-04-13
  • Total pages :384
  • ISBN : 9783030320362
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Summary : ​This book analyzes and evaluates the growing field of light-emitting nanoprobes as contrast agents for in vivo imaging and sensing. It is a comprehensive resource that critically analyzes the state of the art in an interdisciplinary manner, with a special focus on the shift of emission wavelengths into the near-infrared (NIR) spectral region (ranging from 0.7 to 2 microns), which has greatly contributed to the latest advances in biomedical imaging and sensing. This book discusses merits of different contrast agents at nanoscale, and how their unique chemical and structural properties lead to the emission and interaction of light within the NIR window. Both the NIR-emitting materials and various surface modification strategies governing their interactions with the biological system at the “nano” level are discussed. Furthermore, different experimental techniques and protocols for NIR-light-based in vivo imaging and sensing are addressed to shed light on further understanding of the advantages and limitations of each category of these nanoprobes. Assembles the state of the art heretofore appearing in scientific literature into a comprehensive, multi-perspective guidebook on near infrared-emitting nanomaterials in an assortment of biomedical applications; Explains the physical, chemical, and biological phenomena underlying near infrared-emitting nanomaterials for biomedical applications; Presents conceptual and experimental approaches surrounding a unique spectral range of light emission from nanosized contrast agents, while offering a clear explanation of basic and general phenomena regarding the interaction between light and biological tissues, such as absorption, scattering and autofluorescence.

Nanoparticles and their Biomedical Applications

Nanoparticles and their Biomedical Applications
  • Author : Ashutosh Kumar Shukla
  • Publisher :Unknown
  • Release Date :2020-03-06
  • Total pages :286
  • ISBN : 9789811503917
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Summary : Nanotechnology is expected to bring revolutionary changes in a variety of fields. This volume describes nanoparticles and their biomedical applications, and covers metal nanoparticles, metal oxide nanoparticles, rare earth based nanoparticles and graphene oxide nanoparticles. It elaborates on a number of biomedical applications, including therapeutic applications. It addresses the topic of green synthesis, in view of increasing health and environmental concerns.

X-ray Nanochemistry

X-ray Nanochemistry
  • Author : Ting Guo
  • Publisher :Unknown
  • Release Date :2018-06-26
  • Total pages :513
  • ISBN : 9783319780047
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Summary : This book describes the latest developments in the new research discipline of X-ray nanochemistry, which uses nanomaterials to enhance the effectiveness of X-ray irradiation. Nanomaterials now can be synthesized in such a way as to meet the demand for complex functions that enhance the X-ray effect. Innovative methods of delivering the X-rays, which can interact with those nanomaterials much more strongly than energetic electrons and gamma rays, also create new opportunities to enhance the X-ray effect. As a result, new concepts are conceived and new developments are made in the last decade, which are discussed and summarized in this book. This book will help define the discipline and encourage more students and scientists to work in this discipline. These efforts will eventually lead to formation of a full set of physical, chemical and materials principles for this new research field.

Advances in Nanotheranostics I

Advances in Nanotheranostics I
  • Author : Zhifei Dai
  • Publisher :Unknown
  • Release Date :2015-12-15
  • Total pages :336
  • ISBN : 9783662485446
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Summary : This book highlights the recent advances in nanotheranostics from basic research to potential applications, and discusses the modular design and engineering of multiplex nanoparticles including gold nanostructures, luminescent nanoparticles, dendrimers and liposomes. Each chapter demonstrates multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy as new modalities for cancer theranostics. This comprehensive book presents expert views on the latest developments in theranostic nanomedicine. It focuses on potential theranostic applications of multifunctional nanoparticles ranging from identifying noninvasively cancer cells by molecular detection, and visualizing in vivo drug delivery by means of contrast enhanced imaging, to destroying cancer cell s with minimal side effects via selective accumulation at tumor sites, and real-time monitoring therapeutic effectiveness. It also presents an interdisciplinary survey of nanotheranostics and as such is a valuable resource for researchers and students in related fields. Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.

Advances in Magnetic Materials

Advances in Magnetic Materials
  • Author : Sam Zhang,Dongliang Zhao
  • Publisher :Unknown
  • Release Date :2017-02-24
  • Total pages :748
  • ISBN : 9781498706735
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Summary : Advances in Magnetic Materials: Processing, Properties, and Performance discusses recent developments of magnetic materials, including fabrication, characterization and applications in the aerospace, biomedical, and semiconductors industries. With contributions by international professionals who possess broad and varied expertise, this volume encompasses both bulk materials and thin films and coatings for magnetic applications. A timely reference book that describes such things as ferromagnetism, nanomaterials, and Fe, ZnO, and Co-based materials, Advances in Magnetic Materials is an ideal text for students, researchers, and professionals working in materials science. Describes recent developments of magnetic materials, including fabrication, characterization, and applications Addresses a variety of industrial applications, such as aerospace, biomedical, and semiconductors Discusses bulk materials and thin films and coatings Covers ferromagnetism, nanomaterials, Fe, ZnO, and Co-based materials Contains the contributions of international professionals with broad and varied expertise Covers a holistic range of magnetic materials in various aspects of process, properties, and performance

Molecular Imaging

Molecular Imaging
  • Author : Ralph Weissleder
  • Publisher :Unknown
  • Release Date :2010
  • Total pages :1357
  • ISBN : 1607950057
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Summary : The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

Green Synthesis, Characterization and Applications of Nanoparticles

Green Synthesis, Characterization and Applications of Nanoparticles
  • Author : Ashutosh Kumar Shukla,Siavash Iravani
  • Publisher :Unknown
  • Release Date :2018-11-26
  • Total pages :548
  • ISBN : 9780081025802
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Summary : Green Synthesis, Characterization and Applications of Nanoparticles shows how eco-friendly nanoparticles are engineered and used. In particular, metal nanoparticles, metal oxide nanoparticles and other categories of nanoparticles are discussed. The book outlines a range of methodologies and explores the appropriate use of each. Characterization methods include spectroscopic, microscopic and diffraction methods, but magnetic resonance methods are also included as they can be used to understand the mechanism of nanoparticle synthesis using organisms. Applications covered include targeted drug delivery, water purification and hydrogen generation. This is an important research resource for those wishing to learn more about how eco-efficient nanoparticles can best be used. Theoretical details and mathematical derivations are kept to a necessary minimum to suit the need of interdisciplinary audiences and those who may be relatively new to the field. Explores recent trends in growth, characterization, properties and applications of nanoparticles Gives readers an understanding on how they are applied through the use of case studies and examples Assesses the advantages and disadvantages of a variety of synthesis and characterization techniques for green nanoparticles in different situations

Iron Oxide Nanoparticles for Biomedical Applications

Iron Oxide Nanoparticles for Biomedical Applications
  • Author : Sophie Laurent,Morteza Mahmoudi
  • Publisher :Unknown
  • Release Date :2017-09-01
  • Total pages :464
  • ISBN : 0081019254
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Summary : Iron Oxide Nanoparticles for Biomedical Applications: Synthesis, Functionalization and Application begins with several chapters covering the synthesis, stabilization, physico-chemical characterization and functionalization of iron oxide nanoparticles. The second part of the book outlines the various biomedical imaging applications that currently take advantage of the magnetic properties of iron oxide nanoparticles. Brief attention is given to potential iron oxide based therapies, while the final chapter covers nanocytotoxicity, which is a key concern wherever exposure to nanomaterials might occur. This comprehensive book is an essential reference for all those academics and professionals who require thorough knowledge of recent and future developments in the role of iron oxide nanoparticles in biomedicine. Unlocks the potential of iron oxide nanoparticles to transform diagnostic imaging techniques Contains full coverage of new developments and recent research, making this essential reading for researchers and engineers alike Explains the synthesis, processing and characterization of iron oxide nanoparticles with a view to their use in biomedicine

MRI

MRI
  • Author : Brian M. Dale,Mark A. Brown,Richard C. Semelka
  • Publisher :Unknown
  • Release Date :2015-08-06
  • Total pages :248
  • ISBN : 9781119012948
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Summary : This fifth edition of the most accessible introduction to MRI principles and applications from renowned teachers in the field provides an understandable yet comprehensive update. Accessible introductory guide from renowned teachers in the field Provides a concise yet thorough introduction for MRI focusing on fundamental physics, pulse sequences, and clinical applications without presenting advanced math Takes a practical approach, including up-to-date protocols, and supports technical concepts with thorough explanations and illustrations Highlights sections that are directly relevant to radiology board exams Presents new information on the latest scan techniques and applications including 3 Tesla whole body scanners, safety issues, and the nephrotoxic effects of gadolinium-based contrast media

Magnetic Characterization Techniques for Nanomaterials

Magnetic Characterization Techniques for Nanomaterials
  • Author : Challa S.S.R. Kumar
  • Publisher :Unknown
  • Release Date :2017-04-24
  • Total pages :566
  • ISBN : 9783662527801
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Summary : Sixth volume of a 40 volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Magnetic Characterization Techniques for Nanomaterials. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.

Nanotheranostics

Nanotheranostics
  • Author : Mahendra Rai,Bushra Jamil
  • Publisher :Unknown
  • Release Date :2019-11-22
  • Total pages :409
  • ISBN : 9783030297688
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Summary : This book is specifically designed to provide information about various nanocarriers currently developed under the emerging field of nanotheranostics for a sustained, controlled, and targeted co-delivery of diagnostic and therapeutic agents. Diverse theranostic applications of nanotechnology and their limitations are also addressed. It integrates nanobiotechnology with theranostic applications. The combined term nanotheranostics has diverse application particularly in chemotherapy and other infectious diseases.Among other topics addressed are antimicrobial resistance, targeting intra-cellular pathogens, viruses and bacteria, chemotherapy, cancer therapeutics, and inflammatory disorders. This interdisciplinary volume is essential for a diverse group of readers including nanotechnologists, microbiologists, biotechnologists, bioengineering and bioprocess industry.

Practical Approaches to Biological Inorganic Chemistry

Practical Approaches to Biological Inorganic Chemistry
  • Author : Robert R. Crichton,Ricardo O. Louro
  • Publisher :Unknown
  • Release Date :2012-12-31
  • Total pages :336
  • ISBN : 9780444563590
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Summary : The book reviews the use of spectroscopic and related methods to investigate the complex structures and mechanisms of biological inorganic systems that contain metals. Each chapter presents an overview of the technique including relevant theory, clearly explains what it is and how it works and then presents how the technique is actually used to evaluate biological structures. Practical examples and problems are included to illustrate each technique and to aid understanding. Designed for students and researchers who want to learn both the basics, and more advanced aspects of bioinorganic chemistry. Many colour illustrations enable easier visualization of molecular mechanisms and structures Worked examples and problems are included to illustrate and test the reader’s understanding of each technique Written by a multi-author team who use and teach the most important techniques used today to analyse complex biological structures

Radionanomedicine

Radionanomedicine
  • Author : Dong Soo Lee
  • Publisher :Unknown
  • Release Date :2018-05-25
  • Total pages :446
  • ISBN : 9783319677200
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Summary : This book describes radionanomedicine as an integrated medicine using exogenous and endogenous This book describes radionanomedicine as an integrated approach that uses exogenous and endogenous nanomaterials for in vivo and human applications. It comprehensively explains radionanomedicine comprising nuclear and nanomedicine, demonstrating that it is more than radionanodrugs and that radionanomedicine also takes advantage of nuclear medicine using trace technology, in which miniscule amounts of materials and tracer kinetic elucidate in vivo biodistribution. It also discusses exogenous nanomaterials such as inorganic silica, iron oxide, upconversion nanoparticles and quantum dots or organic liposomes labelled with radioisotopes, and radionanomaterials used for targeted delivery and imaging for theranostic purposes. Further, it examines endogenous nanomaterials i.e. extracellular vesicles labelled with radioisotopes, known as radiolabelled extracellular vesicles, as well as positron emission tomography (PET) and single photon emission computed tomography (SPECT), which elucidate the biodistribution and potential for therapeutic success.